Description

1,3-Dibromo-5-Fluoro-4-Methoxy-6-Methyl-2-Nitrobenzene is a highly functionalized, multi-halogenated aromatic compound of significant interest in advanced organic synthesis. Its complex structure, featuring bromine, fluorine, and nitro substituents, makes it a versatile and valuable building block for creating sophisticated molecular architectures. This intermediate is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring halogenated aromatic cores for bioactivity or as a handle for further functionalization.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine and bromine atoms can enhance metabolic stability and binding affinity.
• Material Science Research: Serves as a monomer or building block for developing advanced polymers, liquid crystals, or organic electronic materials with specific optoelectronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions due to its reactive halogen sites.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	1,3-Dibromo-5-Fluoro-4-Methoxy-6-Methyl-2-Nitrobenzene
CAS No.	1357103-68-4
Molecular Formula	C8H6Br2FNO3
Molecular Weight	351.95 g/mol
Synonyms	2-Nitro-1,3-dibromo-5-fluoro-4-methoxy-6-methylbenzene; 5-Fluoro-1,3-dibromo-4-methoxy-6-methyl-2-nitrobenzene; Benzene, 1,3-dibromo-5-fluoro-4-methoxy-6-methyl-2-nitro-; 1,3-Dibromo-5-fluoro-4-methoxy-6-methyl-2-nitrobenzene; DBFMNB (abbreviation)
EINECS	Contact for details

Quality Control

Our production of 1,3-Dibromo-5-Fluoro-4-Methoxy-6-Methyl-2-Nitrobenzene adheres to strict in-process controls and final batch analysis to ensure high purity and consistency. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.