Description

3-Chloro-5,6,7,8-Tetrahydro-Quinoline is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its partially saturated quinoline core, functionalized with a reactive chlorine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting the central nervous system (CNS) or possessing anti-infective properties.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand and Catalyst Development: Used to create novel nitrogen-containing ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Intermediate in the synthesis of organic semiconductors, dyes, and photoactive materials due to its conjugated system.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes.
• Custom Synthesis and Scale-Up: Supplied for contract research organizations (CROs) and custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	3-Chloro-5,6,7,8-Tetrahydro-Quinoline
CAS No.	1356542-52-3
Molecular Formula	C9H10ClN
Molecular Weight	167.64 g/mol
Synonyms	3-Chloro-5,6,7,8-tetrahydroquinoline; 5,6,7,8-Tetrahydro-3-chloroquinoline; 3-Chloro-1,2,3,4-tetrahydroquinoline; 3-Chlorotetrahydroquinoline; Quinoline, 3-chloro-5,6,7,8-tetrahydro-; 3-Chloro-5,6,7,8-tetrahydroquinoline (principal IUPAC name)
EINECS	Contact for details

Quality Control

Our 3-Chloro-5,6,7,8-Tetrahydro-Quinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, GC, and NMR, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.