Description

3-(4-Fluoro-2-Nitrophenoxy)Oxetane is a high-value, multi-functional chemical building block featuring both an oxetane ring and a fluorinated nitroaromatic moiety. This unique structure makes it a critical intermediate for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where it introduces desirable properties like metabolic stability and enhanced binding affinity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for improved bioactivity and environmental persistence.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating high-performance, photo-curable resins and specialty polymers with tailored thermal and mechanical properties.
• Liquid Crystal & OLED Materials: Incorporated into the core structure of electronic display materials to modify electro-optical characteristics.
• Click Chemistry & Bioconjugation: The oxetane ring can be utilized in ring-opening reactions for bioconjugation and labeling applications in diagnostic probe development.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis and medicinal chemistry within university and CRO laboratories.

Basic Information

Product Name	3-(4-Fluoro-2-Nitrophenoxy)Oxetane
CAS No.	1356114-59-4
Molecular Formula	C9H8FNO4
Molecular Weight	213.17 g/mol
Synonyms	3-[(4-Fluoro-2-nitrophenyl)oxy]oxetane; Oxetane, 3-[(4-fluoro-2-nitrophenyl)oxy]-; 4-Fluoro-2-nitrophenyl oxetan-3-yl ether; 3-(4-Fluoro-2-nitro-phenoxy)-oxetane; 1356114-59-4; 3-(4-Fluoro-2-nitrophenoxy)oxetane; 3-(4-Fluoro-2-nitrophenoxy)oxacyclobutane
EINECS	Contact for details

Quality Control

Our production of 3-(4-Fluoro-2-Nitrophenoxy)Oxetane adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for pharmaceutical R&D and other advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.