Description

4-Bromo-2-Propoxy-1-(Trifluoromethoxy)Benzene is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated and alkoxy-substituted benzene structure. This compound is critical for the synthesis of complex molecules, offering a versatile building block for introducing specific bromo, propoxy, and trifluoromethoxy functional groups. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced pesticides and herbicides, leveraging its halogen and ether functionalities.
• Material Science Research: Used in the development of specialty polymers and liquid crystals where its specific aromatic substitution pattern imparts desired electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex biaryl and heterocyclic structures in academic and industrial R&D.
• Fluorine Chemistry Studies: Acts as a valuable substrate for investigating the effects of the trifluoromethoxy group on molecular reactivity and bioavailability.

Basic Information

Product Name	4-Bromo-2-Propoxy-1-(Trifluoromethoxy)Benzene
CAS No.	1355248-26-8
Molecular Formula	C10H10BrF3O2
Molecular Weight	299.09 g/mol
Synonyms	1-Bromo-4-propoxy-2-(trifluoromethoxy)benzene; 4-Bromo-2-propoxy-1-(trifluoromethoxy)benzene; Benzene, 1-bromo-4-propoxy-2-(trifluoromethoxy)-; 2-Propoxy-4-bromo-1-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of 4-Bromo-2-Propoxy-1-(Trifluoromethoxy)Benzene is monitored through in-process controls and final batch analysis to ensure consistency and high purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. Our quality system is designed to support cGMP requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.