Description

3-(2-Chloro-5-Methoxyphenyl)Aniline, Hcl is a high-purity, halogenated aniline derivative supplied as its hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides, leveraging the chloro and methoxy substituents for bioactivity.
• Material Science Research: Used in the creation of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic amine functionality.
• Dye and Pigment Manufacturing: Intermediate for producing specialized azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex amine derivatives.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for medicinal chemistry and process development projects.

Basic Information

Item	Detail
Product Name	3-(2-Chloro-5-Methoxyphenyl)Aniline, Hcl
CAS No.	1355248-17-7
Molecular Formula	C13H13Cl2NO
Molecular Weight	270.15 g/mol
Synonyms	3-(2-Chloro-5-methoxyphenyl)aniline hydrochloride; 2-Chloro-5-methoxy-m-phenylenediamine hydrochloride; 1-Amino-3-(2-chloro-5-methoxyphenyl)benzene hydrochloride; 3-Amino-2'-chloro-5'-methoxy biphenyl hydrochloride; Benzenamine, 3-(2-chloro-5-methoxyphenyl)-, hydrochloride; (3-(2-Chloro-5-methoxyphenyl)phenyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our production of 3-(2-Chloro-5-Methoxyphenyl)Aniline, Hcl adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for GMP-relevant synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.