Description

4-Bromo-2-Ethoxy-1-(Trifluoromethoxy)Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique trifluoromethoxy and bromo substituents, which impart significant electronic and steric properties crucial for developing novel materials and active molecules. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new drug candidates, crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing the trifluoromethoxy pharmacophore.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the benzene core provides structural diversity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes due to its aromatic and halogenated structure.
• Polymer Chemistry: Acts as a monomer or modifier in the production of high-performance polymers with specific thermal and chemical resistance properties.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Stille couplings for carbon-carbon bond formation.
• Chemical Research: Employed in academic and industrial R&D labs as a standard or novel reagent for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	4-Bromo-2-Ethoxy-1-(Trifluoromethoxy)Benzene
CAS No.	1355247-61-8
Molecular Formula	C9H8BrF3O2
Molecular Weight	285.06 g/mol
Synonyms	1-Bromo-4-ethoxy-2-(trifluoromethoxy)benzene; 2-Ethoxy-4-bromo-1-(trifluoromethoxy)benzene; 4-Bromo-2-ethoxy-α,α,α-trifluoroanisole; Benzene, 4-bromo-2-ethoxy-1-(trifluoromethoxy)-; 4-Bromo-2-ethoxy-1-(trifluoromethoxy)benzene (CAS 1355247-61-8)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Ethoxy-1-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.