Description

1-Bromo-2-(Cyclohexanesulfonyl)Benzene is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonyl linker and halogenated aromatic structure. This compound is critical for medicinal chemists in the research and development of novel small-molecule therapeutics, particularly as a versatile building block for constructing complex molecular architectures. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, especially those targeting kinase inhibition or requiring sulfonamide-based pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the bromo and sulfonyl groups contribute to biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Heck, or Buchwald-Hartwig amination for carbon-carbon and carbon-heteroatom bond formation.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and protein-ligand interactions.

Basic Information

Product Name	1-Bromo-2-(Cyclohexanesulfonyl)Benzene
CAS No.	1355247-43-6
Molecular Formula	C₁₂H₁₅BrO₂S
Molecular Weight	303.22 g/mol
Synonyms	2-Bromophenyl Cyclohexyl Sulfone; (2-Bromophenyl)(cyclohexyl)sulfone; Cyclohexyl 2-Bromophenyl Sulfone; 1-Bromo-2-(cyclohexylsulfonyl)benzene; 2-Bromo-1-(cyclohexanesulfonyl)benzene; o-Bromophenyl Cyclohexyl Sulfone; Benzene, 1-bromo-2-(cyclohexylsulfonyl)-; CAS 1355247-43-6
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-(Cyclohexanesulfonyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.