Description

2-Chloro-4-(2-Chloro-4-Methylphenyl)Benzonitrile CAS NO 1355247-42-5 is a specialized benzonitrile derivative featuring a biphenyl-like structure with chloro and methyl substituents. This compound is valued as a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development teams in the pharmaceutical and agrochemical sectors for the synthesis of complex target molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates with biphenyl or substituted aromatic cores.
• Agrochemical Research: Used in the development and synthesis of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis: Acts as a versatile electrophile or coupling partner in cross-coupling reactions (e.g., Suzuki, Negishi) for constructing complex polyaromatic systems.
• Chemical Research: Utilized in academic and industrial R&D for exploring new reaction methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Chloro-4-(2-Chloro-4-Methylphenyl)Benzonitrile
CAS No.	1355247-42-5
Molecular Formula	C14H9Cl2N
Molecular Weight	262.14 g/mol
Synonyms	2-Chloro-4-(2-chloro-4-methylphenyl)benzonitrile; 2-Chloro-4'-(2-chloro-4-methylphenyl)benzonitrile; 2-Chloro-4-(2-chloro-p-tolyl)benzonitrile; 2-Chloro-4-(2-chloro-4-methylphenyl)benzenecarbonitrile; (2-Chloro-4-(2-chloro-4-methylphenyl)phenyl)methanenitrile; Benzonitrile, 2-chloro-4-(2-chloro-4-methylphenyl)-; 1355247-42-5
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(2-Chloro-4-Methylphenyl)Benzonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.