Description

3-(3-Chloro-5-Fluorophenyl)Aniline, Hcl is a high-purity, halogenated aniline derivative used as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique substitution pattern enables precise molecular design. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the research and production of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of advanced polymers and functional materials with specific electronic or optical properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on novel heterocyclic and fluorinated compounds.

Basic Information

Product Name	3-(3-Chloro-5-Fluorophenyl)Aniline, Hcl
CAS No.	1355247-37-8
Molecular Formula	C12H10Cl2FN
Molecular Weight	258.12 g/mol
Synonyms	3-(3-Chloro-5-fluorophenyl)aniline hydrochloride; 3-Amino-3'-chloro-5'-fluorobiphenyl hydrochloride; 3'-Chloro-5'-fluoro-[1,1'-biphenyl]-3-amine hydrochloride; 3-(3-Chloro-5-fluorophenyl)benzenamine hydrochloride; (3-Chloro-5-fluorophenyl)aniline HCl; 3-Chloro-5-fluoro-3'-aminobiphenyl hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-5-Fluorophenyl)Aniline, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.