Description

2-[6-(3,4-Dihydro-2H-Quinolin-1-Yl)-Pyridin-3-Yl]-Ethanol is a high-purity, advanced pharmaceutical intermediate featuring a unique quinoline-pyridine hybrid structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Kinase Inhibitor Development: The quinoline and pyridine motifs make it a valuable precursor for potential kinase inhibitors used in cancer therapy.
• CNS Drug Discovery: Applied in the research of compounds for neurological and psychiatric conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	2-[6-(3,4-Dihydro-2H-Quinolin-1-Yl)-Pyridin-3-Yl]-Ethanol
CAS No.	1355215-10-9
Molecular Formula	C₁₆H₁₈N₂O
Molecular Weight	254.33 g/mol
Synonyms	1-(5-(2-Hydroxyethyl)pyridin-2-yl)-1,2,3,4-tetrahydroquinoline; 2-(6-(3,4-Dihydro-2H-quinolin-1-yl)pyridin-3-yl)ethan-1-ol; Quinoline-Pyridine Ethanol Derivative; 1355215-10-9; 2-[6-(1,2,3,4-Tetrahydroquinolin-1-yl)pyridin-3-yl]ethanol
EINECS	Contact for details

Quality Control

Our 2-[6-(3,4-Dihydro-2H-Quinolin-1-Yl)-Pyridin-3-Yl]-Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.