Description

7-Fluoro-1H-Spiro[Piperidine-4,2-Quinazolin]-4(3H)-One is a sophisticated spirocyclic heterocyclic compound featuring a fused quinazolinone and piperidine structure with a fluorine substituent. This molecule serves as a high-value building block and key intermediate in modern pharmaceutical research and development. It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis to explore new chemical space and optimize lead compounds.
• Chemical Biology Probe Development: Serves as a core scaffold for creating molecular probes to study enzyme function and biological pathways.
• Advanced Organic Synthesis: Employed in academic and industrial R&D for developing novel synthetic methodologies involving spirocyclic and fluorinated compounds.
• Active Pharmaceutical Ingredient (API) Development: Investigated as a precursor in the development and scale-up of new active pharmaceutical ingredients.

Basic Information

Product Name	7-Fluoro-1H-Spiro[Piperidine-4,2-Quinazolin]-4(3H)-One
CAS No.	1355181-90-6
Molecular Formula	C12H12FN3O
Molecular Weight	233.24 g/mol
Synonyms	7-Fluoro-1H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one; 7-Fluoro-1'H-spiro[piperidine-4,2'-quinazoline]-4'(3'H)-one; 7-Fluoro-3H-spiro[2-benzoxazine-4,4'-piperidine]; 7-Fluoro-1H,3'H-spiro[piperidine-4,2'-quinazolin]-4'-one; 1355181-90-6; Spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one, 7-fluoro-; AKOS026714019; ZINC000103048959
EINECS	Contact for details

Quality Control

Our 7-Fluoro-1H-Spiro[Piperidine-4,2-Quinazolin]-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.