Description

(1R)-1-(4-Fluoro-2-Methoxyphenyl)Ethan-1-Amine Hydrochloride is a high-purity chiral amine building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, which is critical for biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the research and development of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used as a building block for creating advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and catalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where precise stereocontrol is required.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in academic and contract research organizations (CROs).
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(1R)-1-(4-Fluoro-2-Methoxyphenyl)Ethan-1-Amine Hydrochloride
CAS No.	1354970-56-1
Molecular Formula	C9H13ClFNO
Molecular Weight	205.66 g/mol
Synonyms	(1R)-1-(4-Fluoro-2-methoxyphenyl)ethanamine hydrochloride; (R)-1-(4-Fluoro-2-methoxyphenyl)ethylamine hydrochloride; (R)-4'-Fluoro-2'-methoxy-α-methylbenzylamine hydrochloride; (R)-1-(4-Fluoro-2-methoxyphenyl)ethan-1-amine HCl; (R)-1-(4-Fluoro-2-methoxyphenyl)ethylammonium chloride; (R)-α-Methyl-4-fluoro-2-methoxybenzylamine hydrochloride; (1R)-1-(4-Fluoro-2-methoxyphenyl)ethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (1R)-1-(4-Fluoro-2-Methoxyphenyl)Ethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.