Description

3-[(2-Chlorophenyl)Methyl]Azetidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1354961-30-0. This compound is a key building block in modern medicinal chemistry, valued for its azetidine scaffold and chlorophenyl moiety which are crucial for developing novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of new drug candidates, particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for clinical research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Used in the research and development of potential therapeutics targeting neurological disorders.
• Oncological Agent Synthesis: Employed in the construction of molecular libraries for screening against various cancer targets.
• Chemical Biology Probes: Acts as a building block for creating tool compounds to study biological pathways and protein function.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical development pipelines.

Basic Information

Product Name	3-[(2-Chlorophenyl)Methyl]Azetidine Hydrochloride
CAS No.	1354961-30-0
Molecular Formula	C10H13Cl2N
Molecular Weight	218.12 g/mol
Synonyms	1-(2-Chlorobenzyl)azetidine hydrochloride; 3-[(2-Chlorophenyl)methyl]azetidine HCl; Azetidine, 3-[(2-chlorophenyl)methyl]-, hydrochloride; 2-Chlorobenzylazetidine hydrochloride; (2-Chlorobenzyl)azetidine hydrochloride; 1-(2-Chlorobenzyl)azetidine HCl; 3-(2-Chlorobenzyl)azetidine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-[(2-Chlorophenyl)Methyl]Azetidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.