Description

2-(Difluoromethoxy)-6-Fluorobenzyl Amine Hcl is a high-purity, fluorinated benzylamine derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing specific fluorinated motifs into target molecules, which can significantly alter their physicochemical and biological properties. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors and CNS-targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the difluoromethoxy and fluorine substituents enhance bioavailability and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials with tailored surface properties.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands for catalysis and molecular recognition applications in fine chemical manufacturing.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research focused on understanding and applying fluorination chemistry.

Basic Information

Product Name	2-(Difluoromethoxy)-6-Fluorobenzyl Amine Hcl
CAS No.	1354951-46-4
Molecular Formula	C8H8ClF3NO
Molecular Weight	235.60 g/mol
Synonyms	2-(Difluoromethoxy)-6-fluorobenzylamine hydrochloride; 1-[[2-(Difluoromethoxy)-6-fluorophenyl]methyl]amine hydrochloride; 6-Fluoro-2-(difluoromethoxy)benzylamine HCl; (2-(Difluoromethoxy)-6-fluorophenyl)methanamine hydrochloride; α-Amino-2-(difluoromethoxy)-6-fluorotoluene hydrochloride; Benzenemethanamine, 2-(difluoromethoxy)-6-fluoro-, hydrochloride; 1354951-46-4
EINECS	Contact for details

Quality Control

Our production of 2-(Difluoromethoxy)-6-Fluorobenzyl Amine Hcl adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for identity, assay, purity, and related substances. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.