Description

3-[(2-Chloro-6-Fluorophenyl)Methyl]Azetidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined stereochemical structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• API Development: Serves as a key chiral building block for the construction of complex molecular architectures in new active pharmaceutical ingredients.
• Preclinical Studies: Employed in the synthesis of compounds for pharmacological evaluation, toxicology testing, and pharmacokinetic profiling.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for exploratory research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	3-[(2-Chloro-6-Fluorophenyl)Methyl]Azetidine Hydrochloride
CAS No.	1354951-33-9
Molecular Formula	C10H12Cl2FN
Molecular Weight	236.11 g/mol
Synonyms	1-(2-Chloro-6-fluorobenzyl)azetidine hydrochloride; Azetidine, 3-[(2-chloro-6-fluorophenyl)methyl]-, hydrochloride (1:1); 3-((2-Chloro-6-fluorobenzyl)azetidine hydrochloride; (2-Chloro-6-fluorophenyl)methylazetidine HCl; 1-(2-Chloro-6-fluoro-benzyl)-azetidine hydrochloride; Azetidine, 1-[(2-chloro-6-fluorophenyl)methyl]-, hydrochloride
EINECS	Contact for details

Quality Control

Our 3-[(2-Chloro-6-Fluorophenyl)Methyl]Azetidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to client specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.