Description

n-[(S)-(4-Nitrophenoxy)Phenoxyphosphinyl]-L-Alanine 2-Ethylbutyl Ester is a chiral organophosphorus compound of significant interest in advanced chemical synthesis. This specialty chemical serves as a critical intermediate or building block for the development of novel, high-value molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and the creation of biologically active compounds.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor research.
• Agrochemical Research: Used in the development of next-generation pesticides and herbicides, leveraging its phosphinyl-alanine ester structure.
• Chemical Biology Probes: Acts as a precursor for activity-based probes used to study enzyme function and mechanism.
• Asymmetric Catalysis Ligand Synthesis: Serves as a starting material for creating sophisticated chiral ligands and catalysts.
• Peptidomimetic Development: Integral in the design and synthesis of peptide analogs with enhanced stability and bioavailability.
• Material Science Research: Investigated for potential use in creating specialized polymers or functional materials.

Basic Information

Product Name	n-[(S)-(4-Nitrophenoxy)Phenoxyphosphinyl]-L-Alanine 2-Ethylbutyl Ester
CAS No.	1354823-36-1
Molecular Formula	C21H25N2O7P
Molecular Weight	448.41 g/mol
Synonyms	(S)-2-[(4-Nitrophenoxy)(phenoxy)phosphorylamino]propanoic acid 2-ethylbutyl ester; L-Alanine, N-[(4-nitrophenoxy)phenoxyphosphinyl]-, 2-ethylbutyl ester; (S)-2-((4-Nitrophenoxy)(phenoxy)phosphorylamino)propanoic acid 2-ethylbutyl ester; 2-Ethylbutyl N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-L-alaninate; Phosphinylalanine ester derivative; Chiral phosphoramidate ester; ABP precursor 1354823-36-1
EINECS	Contact for details

Quality Control

Our production of n-[(S)-(4-Nitrophenoxy)Phenoxyphosphinyl]-L-Alanine 2-Ethylbutyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.