Description

Cyclopropanecarboxylic Acid, 1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]- is a high-value, multi-functional chemical intermediate characterized by its unique pyridine and cyclopropane core structure. This compound is essential for driving innovation in advanced synthesis, offering a versatile scaffold for constructing complex molecules with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and insecticides, leveraging the trifluoromethyl and chloro substituents for bioactivity.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in biochemical research due to its reactive carboxylic acid group and stable heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-
CAS No.	1354746-75-0
Molecular Formula	C10H7ClF3NO2
Molecular Weight	265.62 g/mol
Synonyms	1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)cyclopropanecarboxylic acid; 2-(1-Carboxycyclopropyl)-3-chloro-5-(trifluoromethyl)pyridine; 3-Chloro-5-(trifluoromethyl)-2-pyridinylcyclopropanecarboxylic Acid; 1-(3-Chloro-5-trifluoromethyl-2-pyridyl)cyclopropanecarboxylic Acid; 2-Pyridinecarboxylic acid, 1-(3-chloro-5-(trifluoromethyl)-2-pyridinyl)cyclopropyl-; CPCA-TFMP; [1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]cyclopropyl]formic acid
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting full compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.