Description

Dichloro[1,3-Bis(2,6-Diisopropylphenyl)-2-Imidazolidinylidene][(2-Isopropoxy)(5-Pentafluorobenzoylamino)Benzylidene]Ruthenium(II) is a highly specialized, second-generation Hoveyda-Grubbs type olefin metathesis catalyst. This compound matters for its exceptional activity and stability, enabling efficient and selective carbon-carbon double bond formation in complex synthetic pathways. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel compounds and fine chemicals.

Application

• Ring-Closing Metathesis (RCM): For the efficient synthesis of medium to large cyclic compounds, including macrocycles and heterocycles, crucial in natural product and pharmaceutical synthesis.
• Cross-Metathesis (CM): For the selective coupling of two different olefins to create new molecular architectures and functionalized intermediates.
• Polymer Synthesis: In the production of specialty polymers via ring-opening metathesis polymerization (ROMP) and acyclic diene metathesis (ADMET) polymerization.
• Pharmaceutical Intermediate Manufacturing: For constructing complex, chiral scaffolds in the development of active pharmaceutical ingredients (APIs).
• Agrochemical Research: In the synthesis of novel, biologically active molecules for crop protection and enhancement.
• Fine Chemical Production: For the scalable, cost-effective synthesis of specialty chemicals and flavors & fragrances.
• Academic & Industrial R&D: As a key reagent in methodology development and exploratory synthesis for new materials and catalysts.

Basic Information

Item	Details
Product Name	Dichloro[1,3-Bis(2,6-Diisopropylphenyl)-2-Imidazolidinylidene][(2-Isopropoxy)(5-Pentafluorobenzoylamino)Benzylidene]Ruthenium(II)
CAS No.	1354710-90-9
Molecular Formula	C46H53Cl2F5N3ORu
Molecular Weight	~ 937.90 g/mol
Synonyms	Hoveyda-Grubbs Catalyst 2nd Generation Derivative; Ruthenium, dichloro[1,3-bis(2,6-diisopropylphenyl)-2-imidazolidinylidene][(2-isopropoxy)(5-[(2,3,4,5,6-pentafluorobenzoyl)amino]phenyl)methylene]-; (H2IMes)(pentafluorobenzoylamino-Hoveyda)RuCl2 Catalyst; NHC-Ruthenium Catalyst; Grubbs-Hoveyda Type Catalyst; Olefin Metathesis Catalyst; Z-Selective Ruthenium Catalyst Precursor
EINECS	Contact for details

Quality Control

Our Dichloro[1,3-Bis(2,6-Diisopropylphenyl)-2-Imidazolidinylidene][(2-Isopropoxy)(5-Pentafluorobenzoylamino)Benzylidene]Ruthenium(II) is manufactured under strict quality-controlled conditions to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and elemental analysis. Certificates of Analysis (COA) detailing purity, identity, and performance metrics are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (argon or nitrogen) due to its moisture-sensitive and oxygen-sensitive nature. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	Dark green to brown crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in common organic solvents (DCM, toluene, THF)
Elemental Analysis	Within theoretical limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.