Description

4-[6-(2-Fluoro-Ethoxy)-Quinolin-2-Yl]-Phenylamine is a high-purity, advanced pharmaceutical intermediate characterized by its specific quinoline-based molecular architecture. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly due to its role as a key building block. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new drug candidates.
• Kinase Inhibitor Development: Serves as a key structural component in the research of potential kinase inhibitors for oncology and other therapeutic areas.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to create more complex heterocyclic compounds.

Basic Information

Product Name	4-[6-(2-Fluoro-Ethoxy)-Quinolin-2-Yl]-Phenylamine
CAS No.	1354653-91-0
Molecular Formula	C19H17FN2O
Molecular Weight	308.35 g/mol
Synonyms	4-[6-(2-Fluoroethoxy)-2-quinolinyl]benzenamine; 4-[6-(2-Fluoroethoxy)quinolin-2-yl]aniline; 2-(4-Aminophenyl)-6-(2-fluoroethoxy)quinoline; 4-(6-(2-Fluoroethoxy)quinolin-2-yl)phenylamine; Benzenamine, 4-[6-(2-fluoroethoxy)-2-quinolinyl]-; 1354653-91-0
EINECS	Contact for details

Quality Control

Our 4-[6-(2-Fluoro-Ethoxy)-Quinolin-2-Yl]-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.