Description

3-Nitro-5,6,7,8-Tetrahydro-1,6-Naphthyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1354542-05-4. This compound is a critical building block in the synthesis of novel, small-molecule drug candidates, particularly within medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds for drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Development: Serves as a building block for potential kinase inhibitors, a major class of targeted cancer therapies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and pharmacological studies.

Basic Information

Product Name	3-Nitro-5,6,7,8-Tetrahydro-1,6-Naphthyridine Hydrochloride
CAS No.	1354542-05-4
Molecular Formula	C9H12ClN3O2
Molecular Weight	229.66 g/mol
Synonyms	3-Nitro-5,6,7,8-tetrahydro-1,6-naphthyridine HCl; 1,6-Naphthyridine, 3-nitro-5,6,7,8-tetrahydro-, hydrochloride; 3-Nitro-1,2,3,4-tetrahydro-1,6-naphthyridine hydrochloride; 1354542-05-4; 3-Nitro-5,6,7,8-tetrahydro[1,6]naphthyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Nitro-5,6,7,8-Tetrahydro-1,6-Naphthyridine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.