Description

trans-2-(Benzyloxy)Cyclobutanol is a chiral cyclobutane derivative featuring a benzyl-protected hydroxyl group, serving as a versatile synthetic intermediate in advanced organic chemistry. Its constrained four-membered ring structure and protected alcohol functionality make it a valuable building block for constructing complex, three-dimensional molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for creating molecules with constrained, bioactive ring systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the cyclobutane scaffold can impart unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty monomers and polymers with specific steric and electronic properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including ring-opening and functionalization reactions.

Basic Information

Product Name	trans-2-(Benzyloxy)Cyclobutanol
CAS No.	1354424-66-0
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	trans-2-(Benzyloxy)cyclobutan-1-ol; (1R,2S)-2-(Benzyloxy)cyclobutanol; (1S,2R)-2-(Benzyloxy)cyclobutanol; 2-(Phenylmethoxy)cyclobutanol; Cyclobutanol, 2-(phenylmethoxy)-, trans-; Benzyl trans-2-hydroxycyclobutyl ether; O-Benzyl-trans-2-cyclobutanol
EINECS	Contact for details

Quality Control

Our trans-2-(Benzyloxy)Cyclobutanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.