Description

3-Bromo-7-Nitroquinoline is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the construction of complex molecular architectures in pharmaceutical and agrochemical research. It serves as a critical intermediate for scientists and process chemists in the development of active pharmaceutical ingredients (APIs), functional materials, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactive quinoline scaffold.
• Material Science: Building block for creating organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs) due to its electron-deficient nitro and bromo substituents.
• Chemical Synthesis: Versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution, facilitating the introduction of diverse functional groups.
• Dye & Pigment Industry: Intermediate in the production of specialized nitro- and bromo-substituted quinoline dyes and colorants.
• Academic & R&D: Fundamental research compound for studying heterocyclic chemistry, reaction mechanisms, and structure-activity relationships (SAR).

Basic Information

Product Name	3-Bromo-7-Nitroquinoline
CAS No.	1354221-07-0
Molecular Formula	C9H5BrN2O2
Molecular Weight	253.05 g/mol
Synonyms	7-Nitro-3-bromoquinoline; 3-Bromo-7-nitro-quinoline; Quinoline, 3-bromo-7-nitro-; 1354221-07-0; 3-Br-7-NO2-Quinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-7-Nitroquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.