Description

(S)-3-(4-Chloro-Benzenesulfinyl)-Pyrrolidine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its role as a key precursor for the development of novel active pharmaceutical ingredients (APIs), particularly in asymmetric synthesis. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop or produce enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Used as a ligand or catalyst component in enantioselective reactions to create optically active molecules.
• Agrochemical Research: Serves as a building block for developing novel, enantiomerically pure pesticides and herbicides.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial API production under GMP conditions.
• Academic & Contract Research: A valuable reagent for methodological studies in organic and medicinal chemistry within academic and CRO (Contract Research Organization) settings.
• Fine Chemical Synthesis: Used in the production of complex, high-value specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	(S)-3-(4-Chloro-Benzenesulfinyl)-Pyrrolidine Hydrochloride
CAS No.	1354025-44-7
Molecular Formula	C10H12ClNO2S • HCl
Molecular Weight	282.18 g/mol
Synonyms	(S)-3-[(4-Chlorophenyl)sulfinyl]pyrrolidine hydrochloride; (S)-3-(4-Chlorobenzenesulfinyl)pyrrolidine HCl; (S)-3-(p-Chlorophenylsulfinyl)pyrrolidine hydrochloride; Pyrrolidine, 3-[(4-chlorophenyl)sulfinyl]-, hydrochloride, (3S)-; (3S)-3-[(4-Chlorophenyl)sulfinyl]pyrrolidine hydrochloride; (S)-3-(4-Chloro-phenylsulfinyl)-pyrrolidine hydrochloride; (S)-3-(4-Chlorobenzene-1-sulfinyl)pyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-(4-Chloro-Benzenesulfinyl)-Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.