Description

[(R)-1-(2-Amino-Ethyl)-Pyrrolidin-3-Yl]-Dimethyl-Amine is a high-purity chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its well-defined stereochemistry and bifunctional nature, making it a critical intermediate for constructing complex molecules with specific three-dimensional architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis (e.g., hydrogenation, cross-coupling).
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure pesticides and herbicides.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis Building Block: Provides a versatile scaffold for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis.

Basic Information

Product Name	[(R)-1-(2-Amino-Ethyl)-Pyrrolidin-3-Yl]-Dimethyl-Amine
CAS No.	1354010-29-9
Molecular Formula	C8H19N3
Molecular Weight	157.26 g/mol
Synonyms	(R)-1-(2-Aminoethyl)-3-(dimethylamino)pyrrolidine; (R)-N,N-Dimethyl-1-(2-aminoethyl)pyrrolidin-3-amine; (3R)-1-(2-Aminoethyl)-N,N-dimethylpyrrolidin-3-amine; (R)-3-(Dimethylamino)-1-(2-aminoethyl)pyrrolidine; (R)-DMAPEA; (R)-Aminoethyl-dimethylaminopyrrolidine
EINECS	Contact for details

Quality Control

Our [(R)-1-(2-Amino-Ethyl)-Pyrrolidin-3-Yl]-Dimethyl-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.