Description

[1-(6-Ethoxy-Pyrimidin-4-Yl)-Piperidin-3-Yl]-Methyl-Carbamic Acid tert-Butyl Ester CAS NO 1353984-21-0 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of critical importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, where precise chemical structure and reliable purity are non-negotiable for successful outcomes.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules, particularly for research and development.
• API Synthesis: Used as a building block for constructing the core scaffold of potential new Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Enables medicinal chemists to explore structure-activity relationships (SAR) and optimize lead compounds in drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs specializing in custom synthesis for the pharmaceutical industry.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in related synthetic processes.

Basic Information

Product Name	[1-(6-Ethoxy-Pyrimidin-4-Yl)-Piperidin-3-Yl]-Methyl-Carbamic Acid tert-Butyl Ester
CAS No.	1353984-21-0
Molecular Formula	C18H28N4O3
Molecular Weight	348.44 g/mol
Synonyms	tert-Butyl N-[[1-(6-ethoxypyrimidin-4-yl)-3-piperidyl]methyl]carbamate; 1-(6-Ethoxy-Pyrimidin-4-Yl)-Piperidin-3-Yl]-Methyl-Carbamic Acid tert-Butyl Ester; BOC-Protected 1-(6-Ethoxypyrimidin-4-yl)piperidin-3-ylmethylamine; tert-Butyl (1-(6-ethoxypyrimidin-4-yl)piperidin-3-yl)methylcarbamate; (1-(6-Ethoxy-pyrimidin-4-yl)-piperidin-3-ylmethyl)-carbamic acid tert-butyl ester; CAS 1353984-21-0
EINECS	Contact for details

Quality Control

Our [1-(6-Ethoxy-Pyrimidin-4-Yl)-Piperidin-3-Yl]-Methyl-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and structural identity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity (by HPLC), identity (by IR, NMR), and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.