Description

2-(3-Chloro-4-Fluorophenyl)-4,4-Dimethyl-1,2,3,4-Tetrahydroquinoline-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key synthetic building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for its structural complexity and functional utility in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly in therapeutic areas requiring tetrahydroquinoline-based scaffolds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new molecules with potential biological activity.
• Agrochemical Synthesis: Serves as a building block for developing novel crop protection agents and pesticides.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in laboratory settings.
• Organic Synthesis: Utilized in academic and industrial R&D for constructing complex heterocyclic compounds.

Basic Information

Product Name	2-(3-Chloro-4-Fluorophenyl)-4,4-Dimethyl-1,2,3,4-Tetrahydroquinoline-6-Carboxylic Acid
CAS No.	1353971-43-3
Molecular Formula	C18H17ClFNO2
Molecular Weight	333.79 g/mol
Synonyms	2-(3-Chloro-4-fluorophenyl)-4,4-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid; 4,4-Dimethyl-2-(3-chloro-4-fluorophenyl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid; 1353971-43-3; 6-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-(3-chloro-4-fluorophenyl)-4,4-dimethyl-; Tetrahydroquinoline-6-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 2-(3-Chloro-4-Fluorophenyl)-4,4-Dimethyl-1,2,3,4-Tetrahydroquinoline-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.