Description

1-(2,4-Dichloro-Benzenesulfonyl)-Piperazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific benzenesulfonyl-piperazine structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting various therapeutic areas. It is primarily required by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical suppliers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those with sulfonamide-based pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic agents.
• API Development: Serves as a precursor in the multi-step synthesis of complex target molecules for pre-clinical and clinical trials.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Tool Compound: Potential use in biochemical assays to study enzyme inhibition or receptor modulation.
• Custom Synthesis: Basis for the custom manufacturing of specialized derivatives for proprietary research programs.

Basic Information

Product Name	1-(2,4-Dichloro-Benzenesulfonyl)-Piperazine Hydrochloride
CAS No.	1353966-37-6
Molecular Formula	C10H11Cl3N2O2S
Molecular Weight	337.62 g/mol
Synonyms	1-(2,4-Dichlorophenylsulfonyl)piperazine hydrochloride; Piperazine, 1-[(2,4-dichlorophenyl)sulfonyl]-, hydrochloride (1:1); 2,4-Dichloro-N-(piperazin-1-ylsulfonyl)aniline hydrochloride; 1-(2,4-Dichlorobenzenesulfonyl)piperazine HCl; 1353966-37-6; UNII-Contact for details; Benzenesulfonamide, 2,4-dichloro-N-(1-piperazinyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2,4-Dichloro-Benzenesulfonyl)-Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.