Description

2-(4-Aminomethyl-Piperidin-1-Ylmethyl)-Benzonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a benzonitrile core with a functionalized piperidine moiety. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in neurological and receptor-targeted therapies. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• API Synthesis: Used in multi-step synthetic routes for constructing complex molecules with potential therapeutic activity.
• Medicinal Chemistry Research: Serves as a valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in the development and optimization of robust, scalable manufacturing processes for clinical and commercial drug supply.
• Biochemical Research: May be utilized as a tool compound or ligand in biochemical assays and receptor binding studies.

Basic Information

Product Name	2-(4-Aminomethyl-Piperidin-1-Ylmethyl)-Benzonitrile Hydrochloride
CAS No.	1353959-40-6
Molecular Formula	C15H22N3Cl
Molecular Weight	279.81 g/mol
Synonyms	1-[(2-Cyanophenyl)methyl]-4-(aminomethyl)piperidine hydrochloride; 4-(Aminomethyl)-1-[(2-cyanobenzyl)]piperidine hydrochloride; 2-[(4-(Aminomethyl)piperidin-1-yl)methyl]benzonitrile hydrochloride; 2-(4-Aminomethyl-1-piperidylmethyl)benzonitrile hydrochloride; 1-(2-Cyanobenzyl)-4-(aminomethyl)piperidine HCl; 2-((4-(Aminomethyl)piperidin-1-yl)methyl)benzonitrile hydrochloride; CAS 1353959-40-6
EINECS	Contact for details

Quality Control

Our 2-(4-Aminomethyl-Piperidin-1-Ylmethyl)-Benzonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.