Description

2-[(6-Cyclopropylamino-Pyrimidin-4-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex synthesis pathways. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and antiviral domains.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Custom Synthesis: Serves as a starting material or intermediate for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• API Development: Integral to the development and scale-up processes for new active pharmaceutical ingredients (APIs) prior to clinical trials.
• Biochemical Tool Compound: Can be utilized in the development of biochemical probes for target validation and pathway analysis in biological systems.

Basic Information

Product Name	2-[(6-Cyclopropylamino-Pyrimidin-4-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353956-33-8
Molecular Formula	C19H29N5O2
Molecular Weight	359.47 g/mol
Synonyms	tert-Butyl 2-({[6-(cyclopropylamino)pyrimidin-4-yl]amino}methyl)piperidine-1-carboxylate; 1-Boc-2-({[6-(cyclopropylamino)pyrimidin-4-yl]amino}methyl)piperidine; 1-(tert-Butoxycarbonyl)-2-({[6-(cyclopropylamino)pyrimidin-4-yl]amino}methyl)piperidine; 2-({[6-(Cyclopropylamino)pyrimidin-4-yl]amino}methyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1353956-33-8; BOC-protected cyclopropylaminopyrimidinyl piperidine intermediate
EINECS	Contact for details

Quality Control

Our 2-[(6-Cyclopropylamino-Pyrimidin-4-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.