Description

n-(2-Chloro-Benzyl)-Cyclohexane-1,2-Diamine Hydrochloride is a high-purity, synthetically derived chiral diamine hydrochloride salt. This compound serves as a critical advanced pharmaceutical intermediate and a versatile chiral building block for the development of novel active ingredients. It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical sectors, where precise stereochemistry and reliable quality are paramount.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly for central nervous system (CNS) and antiviral applications.
• Catalyst Ligand Synthesis: Used to construct sophisticated chiral ligands for asymmetric catalysis in fine chemical manufacturing.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	n-(2-Chloro-Benzyl)-Cyclohexane-1,2-Diamine Hydrochloride
CAS No.	1353954-92-3
Molecular Formula	C13H20Cl2N2
Molecular Weight	275.21 g/mol
Synonyms	(1R,2R)-N1-[(2-Chlorophenyl)methyl]cyclohexane-1,2-diamine hydrochloride; (1R,2R)-N-[(2-Chlorophenyl)methyl]cyclohexane-1,2-diamine hydrochloride; (1R,2R)-2-[[(2-Chlorophenyl)methyl]amino]cyclohexanamine hydrochloride; trans-N-(2-Chlorobenzyl)cyclohexane-1,2-diamine hydrochloride; (R,R)-N-(2-Chlorobenzyl)-1,2-diaminocyclohexane hydrochloride; 1,2-Diaminocyclohexane-N-(2-chlorobenzyl) hydrochloride; Chiral Diamine Hydrochloride Derivative
EINECS	Contact for details

Quality Control

Our n-(2-Chloro-Benzyl)-Cyclohexane-1,2-Diamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets exacting research and pharmaceutical-grade standards. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.