Description

4-(3-Bromophenyl)Tetrahydro-2H-Pyran is a high-purity brominated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in providing a versatile scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for lead optimization and scale-up.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bromophenyl moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers where the bromine atom facilitates further functionalization.
• Chemical Biology Probes: Utilized as a core structure for developing molecular probes and tags used in biochemical assay development and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-(3-Bromophenyl)Tetrahydro-2H-Pyran
CAS No.	1353855-35-2
Molecular Formula	C11H13BrO
Molecular Weight	241.13 g/mol
Synonyms	3-Bromo-4-(tetrahydro-2H-pyran-4-yl)benzene; 4-(3-Bromophenyl)tetrahydropyran; Tetrahydro-2H-pyran-4-yl(3-bromophenyl); 3-Bromophenyltetrahydropyran; 4-(3-Bromophenyl)oxane; 3-Bromo-4-(oxan-4-yl)benzene; (3-Bromophenyl)(tetrahydro-2H-pyran-4-yl); 1353855-35-2
EINECS	Contact for details

Quality Control

Our 4-(3-Bromophenyl)Tetrahydro-2H-Pyran is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.