Description

1-Cyclobutoxy-4-Iodo-Benzene is a high-purity, functionalized aromatic compound featuring a cyclobutyl ether and an iodine substituent. This unique structure makes it a valuable advanced intermediate for organic synthesis, particularly in the development of complex molecules. It is primarily used by pharmaceutical R&D and agrochemical laboratories for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially where the iodine atom serves as a handle for further cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Agrochemical Research: Used in creating novel herbicides, fungicides, or insecticides that require a halogenated aromatic core for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis.
• Material Science: Intermediate in the production of organic electronic materials or liquid crystals, where the rigid aromatic-cyclobutyl structure can influence material properties.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	1-Cyclobutoxy-4-Iodo-Benzene
CAS No.	1353777-51-1
Molecular Formula	C10H11IO
Molecular Weight	274.10 g/mol
Synonyms	4-Iodophenyl cyclobutyl ether; Cyclobutyl 4-iodophenyl ether; p-Iodophenyl cyclobutyl ether; 1-Iodo-4-(cyclobutyloxy)benzene; Benzene, 1-cyclobutoxy-4-iodo-; 4-(Cyclobutoxy)iodobenzene
EINECS	Contact for details

Quality Control

Our 1-Cyclobutoxy-4-Iodo-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, purity by HPLC, and identification. We support cGMP and ISO compliant documentation for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.