Description

Chloro[(Tricyclohexylphosphine)-2-(2'-Aminobiphenyl)]Palladium(II) is a highly active and versatile Buchwald-Hartwig amination catalyst, essential for forming C-N bonds in complex organic synthesis. Its value lies in enabling efficient, high-yield cross-coupling reactions under mild conditions, which is critical for streamlining pharmaceutical and advanced material production. This catalyst is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing key molecular scaffolds.

Application

• Pharmaceutical Intermediate Synthesis: Key catalyst for the Buchwald-Hartwig amination in the production of active pharmaceutical ingredients (APIs), especially for nitrogen-containing heterocycles.
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, fungicides, and insecticides that require aryl amine structures.
• Material Science Research: Facilitates the creation of novel organic electronic materials, such as those used in OLEDs and conductive polymers, via C-N coupling.
• Ligand & Catalyst Development: Serves as a precursor or benchmark catalyst in the development of new palladium-based catalytic systems.
• Academic & Industrial R&D: Employed in method development and scale-up studies for new amination and cross-coupling protocols.
• Fine Chemical Production: Enables the synthesis of complex, high-value specialty chemicals and dyes that incorporate aromatic amines.

Basic Information

Product Name	Chloro[(Tricyclohexylphosphine)-2-(2'-Aminobiphenyl)]Palladium(II)
CAS No.	1353658-81-7
Molecular Formula	C30H43ClNPPd
Molecular Weight	590.57 g/mol
Synonyms	Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II); Buchwald-Hartwig Catalyst G3; Pd-PEPPSI-IPentTM Aniline; Palladium(II) chloro[2'-(dimethylamino)-2-biphenylyl](di-tert-butylphosphino) complex; Pd-PEPPSI-IPent; [2-(2-Aminobiphenyl)]chloro(tricyclohexylphosphine)palladium(II); Palladium G3 Catalyst; Chloro(2-dicyclohexylphosphino-2',6'-diisopropoxy-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) (common mis-assignment)
EINECS	Contact for details

Quality Control

Our Chloro[(Tricyclohexylphosphine)-2-(2'-Aminobiphenyl)]Palladium(II) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic activity. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to verify identity, purity, and the absence of deleterious impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. The material is easily oxidized and moisture-sensitive; ensure the container is sealed immediately after use and stored in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Orange to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (Pd content)	≥ 18.0 %
Purity (HPLC)	≥ 98.0 %
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.