Description

3-Hydroxy-1-(4-Methoxyphenyl)Cyclobutanecarboxylic Acid is a high-purity, synthetically derived cyclobutane derivative that serves as a critical advanced pharmaceutical intermediate. Its unique sterically constrained cyclobutane ring and functional group arrangement make it a valuable building block for the synthesis of complex bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) in drug discovery programs.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for target molecules.
• Chemical Synthesis: Employed in the preparation of more complex cyclobutane-containing compounds for various research applications.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	3-Hydroxy-1-(4-Methoxyphenyl)Cyclobutanecarboxylic Acid
CAS No.	1353636-86-8
Molecular Formula	C12H14O4
Molecular Weight	222.24 g/mol
Synonyms	1-(4-Methoxyphenyl)-3-hydroxycyclobutanecarboxylic acid; 3-Hydroxy-1-(4-methoxyphenyl)cyclobutane-1-carboxylic acid; 3-Hydroxy-1-(p-methoxyphenyl)cyclobutanecarboxylic acid; Cyclobutanecarboxylic acid, 3-hydroxy-1-(4-methoxyphenyl)-; CAS 1353636-86-8
EINECS	Contact for details

Quality Control

Every batch of 3-Hydroxy-1-(4-Methoxyphenyl)Cyclobutanecarboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. Our products are produced to meet the exacting standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.