Description

Ethyl 4-Hydroxy-6-(Trifluoromethyl)Quinoline-2-Carboxylate is a high-value, fluorinated quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic combination of a quinoline scaffold with a trifluoromethyl group, enabling the development of compounds with enhanced biological activity and physicochemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in the development of kinase inhibitors, antimicrobials, and anti-inflammatory agents.
• Agrochemical Research: Used in creating novel pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a starting material for the development of organic semiconductors, fluorescent dyes, and other functional organic materials.
• Chemical Synthesis: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Academic & R&D: A valuable reagent for universities and contract research organizations (CROs) exploring new heterocyclic chemistry and fluorine chemistry.

Basic Information

Item	Details
Product Name	Ethyl 4-Hydroxy-6-(Trifluoromethyl)Quinoline-2-Carboxylate
CAS No.	1352935-29-5
Molecular Formula	C₁₃H₁₀F₃NO₃
Molecular Weight	285.22 g/mol
Synonyms	Ethyl 4-hydroxy-6-(trifluoromethyl)-2-quinolinecarboxylate; 6-(Trifluoromethyl)-4-hydroxyquinoline-2-carboxylic acid ethyl ester; 4-Hydroxy-6-(trifluoromethyl)quinoline-2-carboxylic acid ethyl ester; 2-Quinolinecarboxylic acid, 4-hydroxy-6-(trifluoromethyl)-, ethyl ester; Ethyl 4-hydroxy-6-trifluoromethylquinoline-2-carboxylate; CAS 1352935-29-5
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-6-(Trifluoromethyl)Quinoline-2-Carboxylate is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.