Description

tert-Butyl 4-benzyl-3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and diazepane-like scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate for developing new active pharmaceutical ingredients (APIs) with potential for enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for CNS-targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Protease Inhibitor Development: Serves as a core scaffold for designing inhibitors of specific enzymatic targets.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.
• Academic & Institutional Research: Utilized in university and institutional labs for exploratory pharmacology and chemical biology projects.
• Library Synthesis: Employed for generating focused compound libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	tert-Butyl 4-benzyl-3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate
CAS No.	1352925-95-1
Molecular Formula	C20H28N2O4
Molecular Weight	360.45 g/mol
Synonyms	9-Boc-4-benzyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one; tert-Butyl 4-benzyl-3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate; 1-Oxa-4,9-diazaspiro[5.5]undecane-9-carboxylic acid, 4-(phenylmethyl)-3-oxo-, 1,1-dimethylethyl ester; 4-Benzyl-3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester; Boc-protected 4-benzyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-benzyl-3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development from research to commercial scale with quality standards suitable for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.