Description

1-Benzyl-5-Bromo-1H-1,2,4-Triazole is a high-purity, functionalized heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactivity, particularly at the bromine and triazole sites, enabling the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting various enzymes and receptors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand & Catalyst Synthesis: Acts as a versatile scaffold for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Incorporated into polymers and advanced materials to impart specific electronic or mechanical properties.
• Chemical Biology: Employed in the synthesis of probes and tool compounds for studying biological processes and target engagement.
• Custom Synthesis & Scale-Up: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom chemical synthesis projects.

Basic Information

Product Name	1-Benzyl-5-Bromo-1H-1,2,4-Triazole
CAS No.	1352925-80-4
Molecular Formula	C9H8BrN3
Molecular Weight	238.09 g/mol
Synonyms	5-Bromo-1-benzyl-1H-1,2,4-triazole; 1-Benzyl-5-bromo-1,2,4-triazole; 1H-1,2,4-Triazole, 5-bromo-1-(phenylmethyl)-; 5-Bromo-1-benzyl-1,2,4-triazole; Benzyl 5-bromo-1,2,4-triazole; 1352925-80-4
EINECS	Contact for details

Quality Control

Our 1-Benzyl-5-Bromo-1H-1,2,4-Triazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing batch-specific results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.