Description

Methyl 2-Amino-8-Methoxyquinazoline-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a quinazoline core structure, essential for synthesizing complex active pharmaceutical ingredients (APIs). Its value lies in providing a critical, well-defined building block that enables efficient and scalable drug development, ensuring batch-to-batch consistency for downstream processes. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in oncology and other specialized fields.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted anticancer drugs and other specialized small-molecule therapeutics.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates with quinazoline scaffolds.
• API Synthesis: Serves as a critical building block in the commercial-scale production of active pharmaceutical ingredients (APIs) requiring this specific heterocyclic framework.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Utilized in biochemical assays to study enzyme inhibition and other molecular interactions relevant to disease pathways.

Basic Information

Product Name	Methyl 2-Amino-8-Methoxyquinazoline-5-Carboxylate
CAS No.	1352925-69-9
Molecular Formula	C11H11N3O3
Molecular Weight	233.22 g/mol
Synonyms	Methyl 2-amino-8-methoxyquinazoline-5-carboxylate; 2-Amino-8-methoxyquinazoline-5-carboxylic acid methyl ester; 5-Quinazolinecarboxylic acid, 2-amino-8-methoxy-, methyl ester; 8-Methoxy-2-aminoquinazoline-5-carboxylic acid methyl ester; 2-Amino-8-methoxy-5-quinazolinecarboxylic acid methyl ester; Methyl 8-methoxy-2-aminoquinazoline-5-carboxylate; CAS 1352925-69-9
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-8-Methoxyquinazoline-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.