Description

2-Methyl-4-Amino-5,6,7,8-Tetrahydro-Quinolin-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound serves as a critical building block in the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and potential drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of target molecules for various therapeutic areas.
• Fine Chemical Production: Serves as a specialized building block for custom synthesis and contract manufacturing organizations (CMOs).
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2-Methyl-4-Amino-5,6,7,8-Tetrahydro-Quinolin-3-Carboxylic Acid Ethyl Ester
CAS No.	1352723-59-1
Molecular Formula	C₁₃H₂₀N₂O₂
Molecular Weight	236.31 g/mol
Synonyms	Ethyl 2-Methyl-4-amino-5,6,7,8-tetrahydroquinoline-3-carboxylate; 4-Amino-2-methyl-5,6,7,8-tetrahydroquinoline-3-carboxylic acid ethyl ester; 2-Methyl-4-amino-5,6,7,8-tetrahydroquinoline-3-carboxylate ethyl ester; 5,6,7,8-Tetrahydro-2-methyl-4-aminoquinoline-3-carboxylic acid ethyl ester; THQ derivative intermediate; CAS 1352723-59-1
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced analytical techniques, including HPLC, GC, and NMR, to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to a quality management system designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.