Description

Spiro[Bicyclo[2.2.1]Hept[5]Ene-2,2’-[1,3]Dioxolan]-5-Yl Trifluoromethanesulfonate is a specialized, high-purity triflate ester building block designed for advanced organic synthesis. This compound is valued for its role as a reactive intermediate in constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in fine chemical and active pharmaceutical ingredient (API) manufacturing.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in nucleoside and carbohydrate chemistry.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides requiring specific stereochemistry.
• Material Science: Serves as a precursor for monomers or ligands in the creation of specialized polymers and catalysts.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form carbon-carbon bonds.
• Glycosylation Chemistry: Employed in the stereoselective synthesis of complex glycosides and oligosaccharides.
• Asymmetric Synthesis: Utilized in chiral pool synthesis due to its rigid, spiro-fused bicyclic structure.

Basic Information

Product Name	Spiro[Bicyclo[2.2.1]Hept[5]Ene-2,2’-[1,3]Dioxolan]-5-Yl Trifluoromethanesulfonate
CAS No.	1352718-74-1
Molecular Formula	C11H11F3O5S
Molecular Weight	312.26 g/mol
Synonyms	5-Norbornene-2-spiro-2'-(1',3'-dioxolan)-5'-yl trifluoromethanesulfonate; 5-Norbornene-2-spiro-2'-(1',3'-dioxolane)-5'-yl triflate; Spiro[2,4-dioxa-8-azabicyclo[3.3.0]octane-8,2'-norborn-5-ene] Triflate; 5-Trifluoromethanesulfonyloxy-spiro[bicyclo[2.2.1]hept-5-ene-2,2'-[1,3]dioxolane]; Norbornene Spiroketal Triflate; Bicyclo[2.2.1]hept-5-ene-2-spiro-2'-(1',3'-dioxolan)-5'-yl trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Our Spiro[Bicyclo[2.2.1]Hept[5]Ene-2,2’-[1,3]Dioxolan]-5-Yl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.