Description

2-Bromo-7-(Trifluoromethyl) Quinoline is a high-value halogenated quinoline derivative, distinguished by its bromine and trifluoromethyl substituents which confer unique reactivity and physicochemical properties. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the biological activity of the quinoline scaffold.
• Material Science & OLED Development: Acts as a functional unit in the creation of organic light-emitting diodes (OLEDs) and other electronic materials due to its electron-deficient character.
• Ligand & Catalyst Preparation: Employed in the design of novel ligands for transition metal catalysis, facilitating challenging cross-coupling and functionalization reactions.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial R&D laboratories.

Basic Information

Product Name	2-Bromo-7-(Trifluoromethyl) Quinoline
CAS No.	1352443-02-7
Molecular Formula	C10H5BrF3N
Molecular Weight	276.06 g/mol
Synonyms	7-(Trifluoromethyl)-2-bromoquinoline; 2-Bromo-7-trifluoromethylquinoline; Quinoline, 2-bromo-7-(trifluoromethyl)-; 2-Bromo-7-(trifluoromethyl)quinoline; 1352443-02-7
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. Our manufacturing processes adhere to cGMP guidelines where applicable, ensuring reliability for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades Available)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.