Description

7-Iodopyrazolo[1,5-A]Pyridine-3-Carboxylic Acid is a high-value, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a pyrazolopyridine scaffold with both a carboxylic acid and an iodine substituent, enabling diverse derivatization pathways. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for creating novel organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology Probe Development: Utilized in creating tagged molecules or affinity probes for studying biological targets and pathways.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex structures.
• Academic & Contract Research: Employed in universities and CROs for methodological studies and the exploration of new chemical space.

Basic Information

Product Name	7-Iodopyrazolo[1,5-A]Pyridine-3-Carboxylic Acid
CAS No.	1352393-89-5
Molecular Formula	C8H4IN2O2
Molecular Weight	288.04 g/mol
Synonyms	7-Iodopyrazolo[1,5-a]pyridine-3-carboxylic acid; 3-Carboxy-7-iodopyrazolo[1,5-a]pyridine; 7-Iodo-1H-pyrazolo[1,5-a]pyridine-3-carboxylic acid; 7-Iodo-3-pyrazolo[1,5-a]pyridinecarboxylic acid; 1352393-89-5; 7-Iodo-pyrazolo[1,5-a]pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Iodopyrazolo[1,5-A]Pyridine-3-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the exacting standards required for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.