Description

3-(2-Chloro-4-Methylphenyl)Aniline, Hcl is a high-purity organic intermediate, specifically a substituted aniline hydrochloride salt. This compound is valued for its role as a critical building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system or anti-inflammatory pathways.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the chloromethylphenyl aniline structure.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and organic pigments due to its aniline derivative core.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymer materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex aromatic amines.
• Chemical Research & Development: A versatile reagent for academic and industrial research into new synthetic methodologies and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	3-(2-Chloro-4-Methylphenyl)Aniline, Hcl
CAS No.	1352318-55-8
Molecular Formula	C13H13Cl2N
Molecular Weight	254.16 g/mol
Synonyms	3-(2-Chloro-4-methylphenyl)aniline hydrochloride; 2-Chloro-4-methyl-m-phenylenediamine hydrochloride (ambiguous); 3-Amino-2'-chloro-4'-methylbiphenyl hydrochloride; 2-Chloro-4-methyl-3-aminobiphenyl hydrochloride; (2-Chloro-4-methylphenyl)anilinium chloride; 3-(2-Chloro-p-tolyl)aniline HCl; Benzenamine, 3-(2-chloro-4-methylphenyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(2-Chloro-4-Methylphenyl)Aniline, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.