Description

3-(3-Fluoro-4-Methylphenyl)Aniline, Hcl is a high-purity, halogenated aniline derivative, specifically the hydrochloride salt of a fluorinated and methylated aromatic amine. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in sophisticated organic synthesis. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Dye and Pigment Intermediate: Functions as a starting material for producing specialized fluorinated dyes and high-performance pigments.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	3-(3-Fluoro-4-Methylphenyl)Aniline, Hcl
CAS No.	1352318-32-1
Molecular Formula	C13H13ClFN
Molecular Weight	237.70 g/mol
Synonyms	3-(3-Fluoro-4-methylphenyl)aniline hydrochloride; Benzenamine, 3-(3-fluoro-4-methylphenyl)-, hydrochloride; 3'-Amino-3-fluoro-4'-methylbiphenyl hydrochloride; 3-(3-Fluoro-p-tolyl)aniline hydrochloride; 3-Fluoro-4-methyl-[1,1'-biphenyl]-3-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(3-Fluoro-4-Methylphenyl)Aniline, Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specified parameters. We support compliance with ICH guidelines and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.