Description

6-Fluoro-4-Methoxy-Quinoline-2-Carboxylic Acid is a high-purity, synthetically valuable quinoline derivative used as a key building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific fluorine and methoxy substitution pattern enables targeted molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides and herbicides, leveraging its quinoline core for bioactive molecule design.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor or core structure in the synthesis of electron-transport or emissive layer materials for display technologies.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis or as a scaffold for catalyst design in asymmetric synthesis.
• Fluorescent Probe and Dye Synthesis: Acts as a starting material for creating fluorophores and molecular probes used in biochemical sensing and imaging applications.
• Academic and Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the exploration of new chemical reactions.

Basic Information

Product Name	6-Fluoro-4-Methoxy-Quinoline-2-Carboxylic Acid
CAS No.	1351788-61-8
Molecular Formula	C₁₂H₈FNO₃
Molecular Weight	233.20 g/mol
Synonyms	2-Quinolinecarboxylic acid, 6-fluoro-4-methoxy-; 6-Fluoro-4-methoxyquinoline-2-carboxylic acid; 4-Methoxy-6-fluoroquinoline-2-carboxylic acid; 6-Fluoro-4-methoxy-2-quinolinecarboxylic acid; 1351788-61-8; 6-Fluoro-4-methoxyquinoline-2-carboxylate; 6-F-4-MeO-quinoline-2-COOH
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Methoxy-Quinoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.