Description

Methyl Amino(5-Bromo-2-Methoxyphenyl)Acetate Hydrochloride CAS NO 1351581-47-9 is a high-purity, non-racemic synthetic intermediate characterized by its chiral amino acid ester hydrochloride structure. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis of complex, biologically active molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing novel drug candidates and advanced chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and oncology research.
• Peptidomimetic Chemistry: Used in the design and construction of peptide analogs and mimetics due to its protected amino acid ester functionality.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Asymmetric Synthesis: Employed in stereoselective synthesis routes to introduce chiral centers into complex molecular architectures.
• Reference Standard: Utilized as an analytical standard for quality control and method development in regulatory filing and manufacturing.
• Chemical Biology Probes: Acts as a precursor for labeled compounds or probes used in biochemical and cellular assays.

Basic Information

Item	Details
Product Name	Methyl Amino(5-Bromo-2-Methoxyphenyl)Acetate Hydrochloride
CAS No.	1351581-47-9
Molecular Formula	C10H13BrNO3·HCl
Molecular Weight	310.58 g/mol (Free base: 274.12 g/mol)
Synonyms	Methyl 2-Amino-2-(5-bromo-2-methoxyphenyl)acetate hydrochloride; (5-Bromo-2-methoxyphenyl)glycine methyl ester hydrochloride; Methyl (5-bromo-2-methoxyphenyl)glycinate HCl; 2-Amino-2-(5-bromo-2-methoxyphenyl)acetic acid methyl ester hydrochloride; Methyl α-amino-(5-bromo-2-methoxyphenyl)acetate hydrochloride; (R/S)-Methyl 2-amino-2-(5-bromo-2-methoxyphenyl)acetate hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl Amino(5-Bromo-2-Methoxyphenyl)Acetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiomerically pure grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.