Description

1'-Ethyl-6'-Methyl-1'H-Spiro[Piperidine-4,2'-Quinazolin]-4'(3'H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the spiro-quinazolinone class of heterocyclic compounds. Its complex, fused-ring structure makes it a valuable building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily targeted at R&D and process development teams within the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its spirocyclic and quinazolinone pharmacophores.
• API Development: Serves as a critical precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: May be utilized as a reference standard or probe compound in biochemical and pharmacological assays.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical products.

Basic Information

Product Name	1'-Ethyl-6'-Methyl-1'H-Spiro[Piperidine-4,2'-Quinazolin]-4'(3'H)-One
CAS No.	1351398-03-2
Molecular Formula	C15H19N3O
Molecular Weight	257.33 g/mol
Synonyms	1'H-Spiro[piperidine-4,2'-quinazoline]-4'(3'H)-one, 1'-ethyl-6'-methyl-; 1'-Ethyl-6'-methyl-1'H-spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one; Spiro[piperidine-4,2'-quinazolin]-4'(3'H)-one, 1'-ethyl-6'-methyl-; 1351398-03-2; 1'-Ethyl-6'-methylspiro[piperidine-4,2'-quinazolin]-4'(3'H)-one
EINECS	Contact for details

Quality Control

Our 1'-Ethyl-6'-Methyl-1'H-Spiro[Piperidine-4,2'-Quinazolin]-4'(3'H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.