Description

Chloro[(1,3,5,7-Tetramethyl-5-Phenyl-2,4,8-Trioxa-6-Phosphaadamantane)-2-(2-Aminobiphenyl)]Palladium(II) is a highly specialized, air-stable palladium catalyst featuring a bulky, electron-rich phosphine ligand. This compound matters for enabling efficient and selective cross-coupling reactions, which are fundamental to constructing complex molecules in advanced chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate Synthesis: A key catalyst for Buchwald-Hartwig amination and Suzuki-Miyaura cross-coupling reactions in API development.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring C-N and C-C bond formation.
• Materials Science: Facilitates the polymerization and functionalization of organic electronic materials, such as those for OLEDs and conductive polymers.
• Academic & Industrial R&D: An essential tool for methodological development in organic synthesis and catalysis studies.
• Scale-up Process Chemistry: Suitable for optimizing coupling reactions from milligram to kilogram scale due to its stability and defined activity.
• Ligand & Catalyst Screening Libraries: Serves as a pre-formed, well-defined catalyst complex for high-throughput screening applications.

Basic Information

Product Name	Chloro[(1,3,5,7-Tetramethyl-5-Phenyl-2,4,8-Trioxa-6-Phosphaadamantane)-2-(2-Aminobiphenyl)]Palladium(II)
CAS No.	1350851-22-7
Molecular Formula	C31H36ClNO3PPd
Molecular Weight	658.44 g/mol
Synonyms	Buchwald Palladacycle; G3-XantPhos Pd Catalyst; Chloro(2-(2-aminobiphenyl))palladium(II) with BrettPhos Ligand; Pd-PAd2(n-Bu) BrettPhos Precatalyst; Palladium(II) Chloride Complex with 2-(Dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl; (2-Aminobiphenyl)Palladium(II) Chloride Dimer Adduct; Palladium G3 Precatalyst; CAS 1350851-22-7
EINECS	Contact for details

Quality Control

Our Chloro[(1,3,5,7-Tetramethyl-5-Phenyl-2,4,8-Trioxa-6-Phosphaadamantane)-2-(2-Aminobiphenyl)]Palladium(II) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal content, to ensure it meets the high standards required for sensitive catalytic applications. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to minimize oxidation and decomposition. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Palladium (Pd) Content	15.0 - 17.0 %
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.