Description

2-Chloro-n-(1-Isopropylpiperidin-4-Yl)-6-Methoxy-7-(3-(Pyrrolidin-1-Yl)Propoxy)Quinazolin-4-Amine is a high-purity, advanced pharmaceutical intermediate designed for critical research and development applications. This quinazoline derivative is of significant interest for its potential role in the synthesis of novel kinase inhibitors and targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in oncology and signal transduction pathway studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule kinase inhibitors for oncology research.
• Biochemical Research: Used as a reference standard or precursor in enzymatic assays and structure-activity relationship (SAR) studies.
• Drug Discovery & Development: Serves as a core scaffold for medicinal chemists exploring new chemical entities (NCEs) targeting specific protein kinases.
• Preclinical Studies: Employed in the preparation of candidate compounds for in vitro and in vivo pharmacological evaluation.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing specialized compounds for client projects.
• Academic Research: Utilized in university laboratories for fundamental research on cell signaling pathways and drug-receptor interactions.

Basic Information

Item	Details
Product Name	2-Chloro-n-(1-Isopropylpiperidin-4-Yl)-6-Methoxy-7-(3-(Pyrrolidin-1-Yl)Propoxy)Quinazolin-4-Amine
CAS No.	1350752-07-6
Molecular Formula	C24H36ClN5O2
Molecular Weight	462.03 g/mol
Synonyms	2-Chloro-N-[1-(1-methylethyl)-4-piperidinyl]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine; 2-Chloro-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)-N-(1-isopropylpiperidin-4-yl)quinazolin-4-amine; 1350752-07-6; Quinazolin-4-amine, 2-chloro-N-[1-(1-methylethyl)-4-piperidinyl]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]-; 2-Chloro-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-(1-Isopropylpiperidin-4-Yl)-6-Methoxy-7-(3-(Pyrrolidin-1-Yl)Propoxy)Quinazolin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.