Description

1-Bromo-4-Cyclobutoxy-Benzene is a high-value brominated aromatic ether building block of significant interest in advanced organic synthesis. Its core value proposition lies in its unique molecular architecture, which combines a reactive bromine substituent with a strained cyclobutyl ether moiety, enabling the construction of complex, three-dimensional scaffolds. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in medicinal chemistry and functional material design.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for constructing complex ether-linked bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the cyclobutoxy group can influence biological activity and environmental fate.
• Ligand and Catalyst Development: Employed as a building block for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers with specific thermal or optical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems due to its reactive bromine handle for further functionalization.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-Bromo-4-Cyclobutoxy-Benzene
CAS No.	1350640-82-2
Molecular Formula	C10H11BrO
Molecular Weight	227.10 g/mol
Synonyms	4-Bromophenyl cyclobutyl ether; p-Bromophenyl cyclobutyl ether; Benzene, 1-bromo-4-cyclobutoxy-; Cyclobutyl 4-bromophenyl ether; 1-Bromo-4-(cyclobutyloxy)benzene; 4-(Cyclobutoxy)bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Cyclobutoxy-Benzene is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to consistent quality and supply chain reliability makes us a trusted partner for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.